The International Space Station appears to have major sanitation issues.  The main toilet has broken down, resulting in the lack of facilities for 13 astronauts, who have been advised by Mission Control to place an 'out of service' notice on the loo.  Fight Director Brian Smith told reporters "We don't yet know the extent of the problem"

The toilet, a Russian-built unit that cost 19 million dollars, has only been in service for a year and has already broken down once, requiring a replacement pump which was delivered by the shuttle Discovery.